MEASURING KETONES
Ketones are chemicals made by the
liver when the body uses fat for energy. If your diabetes goes severely out of control, ketone levels can
rise excessively in the blood and urine. This can occur with illnesses such as a bad case of the flu or a
gastrointestinal infection or pneumonia. It can also occur when people with type 1 diabetes forget to take
their insulin, if the insulin goes bad, or if their insulin pump malfunctions. High ketone levels with
nausea or vomiting indicates possible DKA, and medical evaluation and hospital treatment may be
necessary.
You can measure ketones in the urine using ketone strips (Acetest, Ketostix), or you can
measure it on a blood drop just like glucose using the Precision Xtra glucose meter (made by Abbott), which not
only measures glucose but also measures one of the blood ketones called beta-hydroxybutyrate using special
strips. Since beta-hydroxybutyrate is the major ketone in DKA, this is the preferred test. Betahydroxybutyrate
levels below 0.6 mmol/L are considered normal, and levels above 1.5 mmol/L are of concern for
DKA.
If you have type 1 diabetes, you should measure your ketones if your blood glucose levels are
unexpectedly high (more than 250 mg/dl) and won’t come down and/or you feel ill with nausea, vomiting, or
dizziness. Table 5-3 summarizes what you should do in these cases.
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