Insulin Glargine
Insulin glargine is human insulin that is modified so that it is soluble in a more acidic
solution. It looks clear in the bottle, and when injected it precipitates in the tissues and is then slowly
released into the bloodstream. Since it is acidic, the manufacturer recommends it should be given as a separate
injection and not mixed in the syringe with the regular or fast-acting insulin analogs. For most people, insulin
glargine works for twenty-four hours. For some individuals (especially small children and small adults who take
low doses of insulin), the effect does not last for twenty-four hours, and in these cases, doses have to be
given twice a day.
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